fallopian tube


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  • Normal

    • architecture
      • mucosa
        • ciliated and secretory epithelia
        • lamina propria
      • muscularis
      • serosa
    • tube segments
      • intramural
      • isthmus
      • ampulla
      • infundibulum
      • fimbria
    • Wolffian/mesonephric duct remnant
      • cuboidal cell tubules
    • Walthard nests
      • urothelial cell tubules
    • epithelium markers
      • WT1+, ER+, PR+

  • Non-neoplastic

  • WHO neoplasms

    • Epithelial
      • malignant
        • serous adenocarcinoma
        • mucinous adenocarcinoma
        • endometrioid adenocarcinoma
        • clear cell adenocarcinoma
        • transitional cell carcinoma
        • SCC
        • undifferentiated carcinoma
      • borderline
        • serous borderline tumor
        • mucinous borderline tumor
        • endometrioid borderline tumor
      • carcinoma in situ
        • STIC
          • p53+
          • Ki67+
        • other types
      • benign
        • papilloma
        • cystadenoma
        • adenofibroma
        • cystadenofibroma
        • metaplastic papillary tumor
        • endometrioid polyp
      • tumor-like epithelial lesions
    • soft tissue
      • leiomyosarcoma
      • leiomyoma
    • mixed epithelial-mesenchymal
      • carcinosarcoma
      • adenosarcoma
    • trophoblastic disease
    • other
    • broad ligament
      • epithelial
        • serous adenocarcinoma
        • endometrioid adenocarcinoma
        • mucinous adenocarcinoma
        • clear cell adenocarcinoma
        • borderline tumor
        • adenoma
        • cystadenoma
      • misc
        • FATWO
        • ependymoma
        • papillary cystadenoma
        • uterus-like mass
        • adenosarcoma
      • mesenchymal
      • metastasis

  • Clinical ddx

    • ectopic pregnancy
    • Peutz Jeghers
      • mucinous metaplasia
    • PID
    • VHL
      • papillary cystadenoma
    • infertility
      • adhesions
    • in utero exposure to DES
      • short, sacculated and convoluted tubes
      • Pinpoint lumen
      • absent plicae

  • TNM (useful for grossing)

    • T1: fallopian tube(s) confined
      • T1a: one tube
      • T1b: both tubes
      • T1c: serosa involvement or malignant peritoneal fluid
    • T2: pelvic extension
      • T2a: uterus or ovary involvement
      • T2b: other pelvic structure involvement
      • T2c: pelvic extension with malignant peritoneal fluid
    • T3: peritoneal implants outside pelvis
      • T3a: microscopic
      • T3b: macroscopic, <= 2cm
      • T3c: > 2cm or N1
    • notes
      • liver capsule metastasis is T3
      • liver parenchymal metastasis is M1
    • regional nodes
      • hypogastric (obturator)
      • common iliac
      • external iliac
      • lateral sacral
      • para-aortic
      • inguinal

  • Staging

    • IA: T1a
    • IB: T1b
    • IC: T1c
    • IIA: T2a
    • IIB: T2b
    • IIC: T2c
    • IIIA: T3a
    • IIIB: T3b
    • IIIC: T3c or N1
    • IV: M1

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    • Benign fallopian tubes, complete cross sections with lumens present bilaterally
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