General

• 30% of lymphomas
• young adults
• site: mediastinum, lymph nodes, esp cervical
• scattered large atypical cells

Staging

• I: single node or structure (spleen, thymus, waldeyer ring)
• II: 2+ ipsilateral nodes
  • mediastinum is single site
  • hilar nodes are lateralized
  • II2 = 2 sites, II3 = 3 sites, etc
• III: contralateral nodes
  • III1
  • III2: paraaortic, iliac or mesenteric nodes
• IV: extranodal involvement

classic Hodgkin lymphoma

NLPHL