yolk sac tumor


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  • Clinical

    • testicular
      • age: infants, children, and postpubertal males
    • AFP elevated
  • Histology patterns

    • microcystic, reticular
    • macrocystic
    • solid
    • glandular-alveolar (looks like lung alveoli)
    • endodermal sinus (Schiller-Duval bodies)
    • papillary
    • myxomatous
    • polyvesicular vitelline
    • hepatoid
    • enteric (resembles glands)
  • Stains

    • AFP+, but can be weak or negative
    • LMWCK+