Histology

• zonal necrosis: acetaminophen, halothane, INH, phenytoin
• cholestasis: steroids, estrogen
• cholestatic hepatitis: abx
• macrovesicular steatosis: EtOH, MTX, steroids, TPN
• microvesicular steatosis: valproate, tetracycline
• steatohepatitis: amiodarone
• cirrhosis: MTX, INH, enalapril
• granulomas: sulfonamides