papillary necrosis


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  • Clinical

    • diabetes mellitus
    • urinary tract obstruction
    • acute pyelonephritis
    • analgesic abuse
    • sickle cell disease
    • hypoxia
    • dehydration

  • Gross

    • papillary form: necrosis in tip of pyramid
    • medullary form: necrosis in center of pyramid

  • Histology

    • acute: coagulative necrosis, rim of PMNs and histiocytes
    • chronic: fibrosis, ghost outlines, hemosiderin, calcifications
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