nasopharyngeal carcinoma


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  • Clinical

    • age 40-60
    • male > female
    • Asians, North Africans, Eskimos
    • strong EBV association

  • Names

    • official: nasopharyngeal carcinoma
    • encompasses
      • SCC
      • nonkeratinizing carcinoma
      • basaloid squamous carcinoma
    • synonyms
      • lymphoepithelioma

  • Histology

    • undifferentiated nasopharyngeal carcinoma
      • aka: lymphoepithelial carcinoma
      • Regaud type: tumor nests, fibrous stroma
      • Schmincke type: tumor sheets, inflammatory infiltrate
    • nonkeratizing SCC
    • Keratinizing SCC

  • Stains

    • CK+
    • CK5/6+
    • EBV+ in a third
    		•