low grade neoplasm

Expand All | Collapse All
  • Clinical

    • cystoscopy dx trumps cytology (cytology not as reliable)
    • cytologic dx only meaningful for upper tract specimen where scope can't reach
  • Entities

    • papilloma (rare, young pt, never recur)
    • PUNLMP
    • low grade urothelial carcinoma
  • Papilloma Cytology

    • no atypia
    • papillary architecture
    • unable to dx by cytology unless papillary fronds present
  • PUNLMP and LG UC Cytology

    • cell clusters with irregular edges
    • papillary fragments (fibrovascular core is diagnostic but rare)
    • high NC ratio
    • irregular nuclear membrane
    • homogeneous cytoplasm