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ENT
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thyroid
follicular adenoma
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Gross
submit entire capsule
Histology
encapsulated
no capsule invasion
architecture
trabecular
solid
microfollicular
macrofollicular
uniform cytology
variants
Hurthle cell adenoma
atypical adenoma
toxic adenoma
Stains
TTF1+
thyroglobulin+
cytokeratin+
Ddx
follicular carcinoma
capsular invasion
nodular hyperplasia
no or incomplete capsule
does not compress surrounding thyroid tissue
encapsulated follicular variant of papillary carcinoma
has papillary carcinoma nuclear features
medullary carcinoma
calcitonin+
parathyroid
PTH+
TTF1-
Associations
iodine deficiency
Cowden disease
hamartoma
PTEN