cholangiocarcinoma


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  • Clinical

    • encompasses all bile duct carcinomas
    • can be intrahepatic or extrahepatic
    • most commonly adenocarcinoma

  • Bile duct adenocarcinoma

    • architecture: infiltrative glands. Can also be micropapillary, acinar, or cord like
    • cytology: small-medium cells, cuboidal, columnar, can be pleomorphic
    • desmoplasia

  • Other carcinomas

    • mucoepidermoid carcinoma
    • lymphoepithelioma like carcinoma
    • sarcomatous cholangiocarcinoma
    • see gallbladder for other types

  • Ddx

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