autoimmune hepatitis


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  • Clinical

    • 70% female
    • type I autoimmune labs: hyper IgG, ANA, anti smooth muscle
    • other types: II (anti LKM), III (anti SLA)

  • Histology

    • interface hepatitis (lymphoplasmacytic, extending to periportal)
    • prominent plasma cells in clusters
    • regenerative hepatocyte rosettes
    • fibrosis as disease progresses
    • steroids can rid of inflammation
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