Apps
Surgpath
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ENT
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nose
angiofibroma
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Clinical
male
age 6-29
nasal obstruction, epistaxis
locally aggressive
Histology
blood vessels
stroma varies
loose edematous
dense collagenous
can have stellate, spindle, angulated cells
Stains
CD31+ in endothelial cells
beta catenin+ (>75%)
vimentin+ in stroma
Ddx
pyogenic granuloma
solitary fibrous tumor
Kaposi sarcoma
angiosarcoma