anaplastic astrocytoma


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  • Clinical

    • mean age 45
    • site: hemispheres
    • can be de novo or arise from diffuse astrocytoma
    • progresses to glioblastoma
    • WHO grade III

  • Histology

    • hypercellular
    • mitosis
    • atypia
    • lack of necrosis or microvascular proliferation

  • Stains

    • GFAP+
    • Ki67 5-10%
    		•