Wegener disease


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  • Clinical

    • chronic nasal ulcer

  • Histology

    • geographic biocollagenolytic necrosis (blue, granular debris)
    • other Wegener features (vasculitis, granuloma) not apparent in the nose

  • Immunofluorescence

    • cANCA+

  • Ddx

    • infection
    • microscopic polyangiitis
    • Churg-Strauss syndrome
    • lymphoma
    • cocaine use
    		•