Negative for malignancy

• Normal
  • lymphocytes
  • monocytes
  • rare cells
    • choroid plexus
    • ependymal cells
    • brain fragments
    • germinal matrix
    • chondrocytes
    • bone marrow
• Abnormal
  • macrophages
    • meningitis
    • SAH
    • IVH
    • infarction
    • post-treatment
    • Multiple sclerosis
  • plasma cells
    • viral meningitis
    • Lyme disease
    • tuberculosis
    • cysticercosis
    • syphilis
    • multiple sclerosis
  • neutrophils
    • peripheral blood contamination
    • bacterial meningitis
    • CMV
    • toxoplasma
    • early viral meningitis
  • eosinophils
    • parasites
    • coccidioides
    • VPS
    • RMSF
    • malignancy
    • medications
• Infection
  • bacterial meningitis
  • viral encephalitis
  • aseptic meningitis
    • viral
    • bacterial
    • fungal
    • autoimmune
    • drugs
  • cryptococcus
  • toxoplasma
  • cysticercosis
  • angiostrongyliasis
  • ameba

Atypical cells present

Suspicious for malignancy

Positive for malignancy

• primary CNS
  • lymphoma
  • medulloblastoma
  • glioma
    • astrocytoma
  • ependymoma
  • oligodendroglioma
  • ATRT
  • choroid plexus tumor
  • pineal tumor
  • GCT
• metastasis
  • lung cancer
  • breast cancer
  • melanoma
• leukemia
  • acute lymphoblastic leukemia
  • AML
  • CLL
  • Burkitt
  • plasma cell neoplasm
• MPN