mediastinal large B cell lymphoma


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  • Names

    • primary mediastinal (thymic) large B cell lymphoma

  • Clinical

    • median age 35
    • mediastinal mass

  • Stains

    • positive: B markers, CD30 (80%, weak), MUM1 (75%), Cd23 (70%)
    • negative: Ig

  • Molecular

    • 9p24 gain (75%)
    • 2p15 gain (50%)
    • Xp11.4-21 gain (33%)
    • Xq24-26 gain (33%)
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