well differentiated liposarcoma


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  • Names

    • well differentiated liposarcoma
    • atypical lipomatous tumor

  • Clinical

    • middle aged, peak in 60s
    • site: deep limbs, esp thighs, retroperitoneum, paratesticular, mediastinum

  • Histology

    • mostly mature fat
    • scattered hyperchromatic stromal cells
    • rarely can have heterologous elements
      • bone
      • smooth, skeletal muscle

  • Subtypes

  • Molecular

    • MDM2 amplification
    		•