translocation RCC


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  • Clinical

    • Xp11.2, TFE3
    • predominantly children, young adults
    • ASPL-TFE3 associated with advanced age
  • Histology

    • architecture: papillary, nested
    • cytology: clear cells, granular eosinophilic
    • psammoma bodies
  • Stains

    • TFE3+
    • RCC, CD10+