synovial sarcoma


Expand All | Collapse All

  • Clinical

    • age: young adults
    • site: extremities, head/neck, intrathoracic, and other sites

  • Histology

    • monophasic
      • fascicles
      • spindle cells
    • biphasic
      • epithelial cells
        • oval nuclei, abundant cytoplasm
        • glandular spaces, can be cleft/hemangiopericytoma-like
        • can also form papillary structures
      • spindle cells
    • 1/3 will have calcifications +/- ossification
    • Poorly differentiated SS has areas of high cellularity, mitosis, necrosis

  • Stains

    • CK (7, 19), EMA, vimentin+

  • Ddx

    • metastasis
    • other sarcoma
    		•