Cytology

• architecture is macrofollicle fragments
  • sheets, uniform spacing between cells
  • lack of microfollicles (aggregates)
• nuclear atypia
  • size variation, hyperchromasia
  • smudgy chromatin
  • grooves, pseudoinclusions
• enlarged cells but normal NC ratio
• naked nuclei
• Hurthle cell change
• cytoplasmic vacuolization