pleuropulmonary blastoma


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  • Clinical

    • child, infant
    • lung, pleura
  • Histology

    • type I
      • multicystic
      • lining: respiratory
      • wall: small primitive undifferentiated cells
    • type II
      • sheets, plaques, nodules
      • small primitive cells
      • embryonal rhabdomyosarcoma
      • spindle cells
    • type III
      • solid
      • sarcomatous cells
  • Stains

    • vimentin+
    • CK stains respiratory lining only
    • muscle specific actin+