papillary adenoma


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  • Clinical

    • most common epithelial neoplasm of kidney
    • 10% of adults, 40% of elderly, 33% of acquired renal cystic disease
    • associations: long term hemodialysis

  • Gross

    • small
    • well circumscribed

  • Histology

    • architecture: papillary, tubular, tubulopapillary
    • benign cytology, may have nuclear grooves
    • type 1: single layer small cells with scant cytoplasm
    • type 2: pseudostratified, eosinophilic cytoplasm
    • psammoma bodies, foamy macrophages

  • Molecular

    • y loss
    • trisomy 7 and 17
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