osteochondroma


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  • Clinical

    • most common bone tumor
    • site: metaphysis of distal femur, upper humerus, upper tibia, fibula. Less commonly ilium, scapula.
  • Histology

    • architecture: cartilage capped bony projection containing marrow. Has a bony stalk.
    • layers: perichondrium, cartilage, bone
      • perichondrium is continuous with periosteum
      • endochondral ossification at base of cartilage
    • benign cytology: low cellularity, no mitosis, no atypia
  • Ddx

    • chondrosarcoma
      • lacks stalk
      • cartilage infiltrates soft tissue
    • bunions and osteophytes
      • lack marrow cavity