ossifying fibromyxoid tumor


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  • Clinical

    • median age: 50
    • site: extremities (70%), trunk, head/neck, retroperitoneum
  • Histology

    • architecture: lobules, nests, cords, trabecula
    • cytology: round to oval cells, low mitosis (< 1 per 10 hpf)
    • stroma: fibromyxoid
    • 80% have partial shell of bone
  • Stains

    • positive: vimentin, S100 (70%)