nodal MZL


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  • Clinical

    • criteria: node confined, no extranodal or splenic disease
    • site: node, marrow, blood

  • Morphology

    • node: pale marginal zone tumor cells (surrounds follicles)
    • tumor cells: centrocyte-like, monocytoid

  • Stains

    • positive: BCL2
    • negative: CD5, CD23, CD10, BCL6, cyclinD1
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