myxoid liposarcoma


Expand All | Collapse All

  • Names

  • Clinical

    • 1/3 of all liposarcoma
    • site: deep extremities, 2/3 in thigh

  • Histology

    • signet ring lipoblasts
    • round-oval stromal cells
    • myxoid stroma, mucin pools that look like pulmonary edema
    • delicate chicken-wire vasculature
    • round cell variant has sheets of primitive high NC ratio round cells

  • Stains

    • S100 diffusely+

  • Molecular

    • DDIT3-FUS = CHOP-TLS = t(12;16)(q13;p11)
    		•