myxoid chondrosarcoma

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  • Clinical

    • median age: 60
    • soft tissue site: proximal extremities and girdles
  • Histology

    • architecture: multinodular with fibrous septa
    • cytology: epithelioid or spindled, pink granular vacuolated cytoplasm, oval nuclei
    • stroma: myxoid or chondromyxoid, hemorrhage is common
    • can have areas of sheets of high grade epithelioid cells
    • cellular variant: diffusely cellular, more mitosis
  • Stains

    • positive: vimentin