metanephric adenofibroma


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  • Clinical

    • polycythemia
  • Histology

    • highly cellular, tightly packed
    • acini, branching tubular, looks solid due to tight packing
    • cytology: small blue cels, bland, no nucleoli
    • psammoma bodies
    • stroma
      • adenoma: scant or loose edematous
      • adenofibroma: spindle cells of metanephric stromal tumor
  • Stains

    • WT1+, CD57+
    • adenofibroma spindle cells: CD34+
    • CK7-, EMA-