mesonephric adenocarcinoma


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  • Clinical

    • arise from mesonephric remnants
    • location: lateral to posterior cervix or circumferential

  • Histology

    • tubular glands
    • cuboidal epithelium
    • lumen: pink hyaline secretions, necrotic debris
    • atypia, mitosis
    • background mesonephric remnant hyperplasia
    • other patterns: soid, papillary, ductal, retiform

  • Stains

    • CK+, EMA+, CD10+
    • calretinin, vimentin +/-
    • ER/PR negative
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