malakoplakia


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  • Clinical

    • middle aged women
    • recurrent UTI
    • bladder involvement is much more common
    • pulmonary form is associated with Rhodococcus

  • Gross

    • dilated pelvis, calyces
    • soft yellow-brown nodules

  • Histology

    • sheets, nodules
    • eosinophilic histiocytes (von Hansemann histiocytes)
    • basophilic target-like inclusions (Michaelis-Gutmann bodies)
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