lymphocytic esophagitis


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  • Histology

    • intraepithelial lymphocytes

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    • Suspect reflux: Squamous mucosa with patchy increase in intraepithelial lymphocytes and reactive changes, suggestive of gastroesophageal reflux
    • Not sure:
      • increased intraepithelial lymphocytes in the esophagus is a nonspecific finding
      • given the presence of associated neutrophils and rare eosinophils, severe reflux is a possibility
      • the differential includes infection, allergy or adverse drug reaction, and idiopathic lymphocytic esophagitis
      • A GMS stain is ___
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