ischemic colitis


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  • Clinical

    • age: 50+
    • location: splenic flexure, descending colon, sigmoid
    • imaging
      • thumbprinting on barium enema
      • target lesions on CT

  • Gross

    • ulcers
    • can have pseudomembranes
    • can have stricture

  • Histology

    • superfical mucosal necrosis
    • crypt atrophy, regenerative atypia
    • hyalinized lamina propria
    • lack of prominent inflammation

  • Stains

    • trichrome stains lamina propria hyaline

  • Ddx

    • C difficile
      • no lamina propria hyaline or trichrome staining
      • no crypt atrophy
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