intraductal carcinoma


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  • Clinical

    • controversial category
    • overlaps with cribriform high grade PIN
    • can't distinguish from intraductal spread of prostate adenocarcinoma

  • Histology

    • multiple cribriform glands with prominent atypia and comedo necrosis

  • Stains

    • intact basal cell layer (p63)

  • Ddx

    • PIN
    • prostate adenocarcinoma with intraductal spread
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