iatrogenic immunodeficiency


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  • Types

    • Crohns, infliximab in young pt: hepatosplenic T cell lymphoma, fatal
    • Psoriasis on MTX: polymorphic LPD, peripheral T cell lymphoma
    • autoimmune dz
      • MTX: DLBCL, Hodgkin lymphoma
      • infliximab: DLBCL, others
      • other B, T, Hodgkin (CD20-/30+/15+), and Hodgkin-like lesions (CD20+/30+/15-)
    • EBV: Hodgkin (80%), Hodgkin-like, polymorphic PLD, DLBCL (25%)
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