hydroa vacciniforme like lymphoma


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  • Clinical

    • children and adolescent
    • Asian predominance, also Mexican, central and south American
    • sun sensitivity, mosquito sensitivity
    • face and extremities
    • EBV association
    • progresses to systemic involvement (fever, lymphadenopathy, organomegaly)

  • Histology

    • skin infiltration by small-medium atypical cells
    • angiocentric, angioinvasive, necrosis

  • Stains

    • positive: EBV, TIA1, CD2
    • variable: CD8, CD56
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