hibernoma


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  • Clinical

    • mean age 38
    • site: thigh, trunk, arm, head/neck
    • size: 1-24 cm, median 9 cm
  • Histology

    • multivacuolated brown fat cells, granular cytoplasm
    • myxoid variant: myxoid stroma
    • spindle cell variant: bland spindle stroma
  • Stains

    • S100+
    • CD34+ in spindle cells (spindle variant)
  • Molecular

    • 11q13 rearrangement