hepatosplenic T cell lymphoma


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  • Clinical

    • associations: chronic immunosuppression
    • site: splene, liver, marrow, spares node
  • Morphology

    • medium sized lymphoid cells
    • sinusoidal infiltration
  • Stains

    • positive: CD3, TCRD1, CD56+/-
    • negative: TCRAB, CD5, CD4, CD8-/+