giant cell angiofibroma


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  • Clinical

    • site: orbital region, head and neck
      • can also occur in other sites including retroperitoneum
    • size: ~3 cm, up to 10 cm

  • Histology

    • multinucleated giant stromal cells
    • thick-walled vessels
    • round to spindle cells
    • collagenous/myxoid stroma, focal sclerosis

  • Stains

    • stromal cells: CD34+, CD99+, BCL2+/-
    		•