follicular neoplasm


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  • Clinical

    • Category 4 in Bathesda
    • FNA is screening but not diagnostic for follicular carcinoma
    • unable to differentiate follicular carcinoma (capsule invasion) vs adenoma
    • completion thyroidectomy if histology shows carcinoma
  • Entities

    • Follicular adenoma
    • Follicular carcinoma
  • Cytology

    • crowded aggregates, overlapping, microfollicles, trabecula
    • enlarged cells
    • scant colloid
    • suprisingly, nuclear atypia/mitosis is quite uncommon
    • can have minor component of macrofollicles
  • Ddx

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    • (suspicious for a) follicular neoplasm