embryonal rhabdomyosarcoma


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  • Clinical

    • site: head and neck, genitourinary, extremities
    • age < 15

  • Histology

    • rhabdoid cells in various stages of development
      • rhabdomyoblasts: stellate
      • intermediate: elongated
      • mature: striated
    • myxoid stroma

  • Variants

  • Stains

    • primitive cells: vimentin
    • intermediate cells: desmin, actin
    • mature cells: myoglobin, myosin

  • Molecular

    • 11p15 loss
    		•