complete mole



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  • Karyotype

    • diploid
    • 90% is 46, XX (one sperm fertilizing empty egg)
    • 10% is 46, XY (two sperms fertilizing empty egg)
  • Histology

    • hydropic, cavitated villi
    • trophoblast hyperplasia with atypia
    • lack of fetal tissue, gestational sac, amnion, umbilical cord
  • Stains

    • p57 negative