clear cell tumor


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  • Clinical

    • extremely rare
    • associations: tuberous sclerosis, lymphangioleiomyomatosis
    • solitary peripheral

  • Names

    • clear cell tumor
    • PEComa

  • Histology

    • clear cells or eosinophilic cells
    • bland cytology (lack necrosis, mites)

  • Stains

    • CK-
    • S100, HMB45+
    • glycogen: PAS+, diastase sensitive

  • Ddx

    • clear cell carcinoma
      • CK+
    • melanoma
      • atypia
    • clear cell sarcoma
      • atypia
    • granular cell tumor
      • S100+
      • HMB45-
    		•