chronic pyelonephritis


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  • Clinical

    • recurrent or smoldering infection
    • obstruction, reflux
    • reflux nephropathy: vesicoureteral reflux, compound pyramid
    • obstructive pyelonephritis: obstruction +/- infection
  • Gross

    • small kidneys
    • reflux: polar scars in pyramid
    • obstructive: diffuse scars
  • Histology

    • tubular atrophy, pink colloid casts in tubules (thyroidization)
    • interstitial fibrosis
    • chronic inflammation
    • glomerulosclerosis