basal cell carcinoma


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  • Clinical

    • elderly

  • Histology

    • malignant features
      • infiltrative
      • extraprostatic extension
      • perineural invasion
      • necrosis
      • desmoplasia
    • architectural patterns
      • basaloid nests with peripheral palisading and comedo necrosis
      • florid basal cell hyperplasia
      • adenoid cystic-like

  • Stains

    • positive: 34BE12, BCL2, Ki-67
    • variable: S100
    • negative: SMA

  • Ddx

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