adenosarcoma


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  • Clinical

    • age: 15-90, median 58
    • associations: tamoxifen
    • polypoid mass protrudes through os
  • Histology

    • benign epithelial component
      • may have metplasia
    • sarcomatous mesenchymal component
      • homologous: smooth muscle, sex cord-like elements
      • heterologous: striated muscle, cartilage, fat
    • resembles phyllodes tumor
  • Stains

    • epithelial components: CK
    • mesenchymal: CD10, smooth muscle