adenocarcinoma


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  • Clinical

    • nonsmokers like to get this
    • peripheral nodule

  • Subtypes

  • Stains

    • panCK+
    • CK7 > CK20
    • TTF1+
    • Mucinous BAC: CK20+, TTF1-, CDX2+
    • Panel
      • mucin
      • panCK
      • 2 adeno markers (CEA, CD15, MOC31)
      • TTF1
      • 2 mesothelioma markers (calretinin, CK5/6)

  • Molecular

    • y loss
    • +1, +7
    • 1q overrepresentation
    • 3p del
    • K-ras
    • p53

  • Ddx

    		•