acquired RCC


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  • Clinical

    • ESRD on dialysis

  • Histology

    • background ESRD: cysts, glomerulosclerosis, tubular atrophy, interstitial fibrosis
    • architecture: solid, papillary, acinar, cribriform, tubulocystic
    • cytology: pink vacuolated cytoplasm
    • calcium oxalate crystals

  • Stains

    • positive: CK, CD10, RCC, racemase
    • negative: CK7 (at most focal)
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