Spitz nevus


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  • Clinical

    • children
    • pink lesion on head
  • Histology

    • hyperkeratosis, hypergranulosis, pseudoepitheliomatous hyperplasia
    • nests: vertical, at junction, has clefts, large spindle and epithelial cells
    • Kamino bodies (pink pools)
    • benign features
      • has maturation and dispersion at base
      • lacks deep mitosis or pigment
  • Stains

    • HMB45 top heavy
    • S100+