Rosai Dorfman disease


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  • Clinical

    • any age, usually 10-20s
    • localized lymphadenopathy
    • self limited if not immunocompromised
    • may have an underlying lymphoma

  • Histology

    • sinus histiocytosis
    • hemophagocytosis, emperipolesis

  • Stains

    • pos: CD68, S100
    • neg: CD1a
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