PNET


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  • Names

    • Ewing sarcoma
    • PNET
    • primintive neuroectodermal tumor

  • Histology

    • small round blue cells
    • rosette/pseudorosette formation

  • Stains

    • CD99, NSE

  • Molecular

    • t(11;22) = EWS-FLI1
    • EWS 22q12, FLT1 11q24
    • 5% have other EWS fusions: ERG (21q12), ETV1 (7p22)
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