Apps
Hemepath
→
neoplastic
→
histiocytic and dendritic
Langerhans cell sarcoma
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Clinical
site: multifocal extranodal (skin, bone) > nodal
Morphology
pleomorphic
mitosis > 50 per 10hpf with atypical forms
Stains
same as LCH (CD1a, S100, langerin)